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Non-acid Reflux: When It Matters and Approach to Management.

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Non-acid Reflux: When It Matters and Approach to Management. Current gastroenterology reports Zikos, T. A., Clarke, J. O. 2020; 22 (9): 43

Abstract

This narrative review focuses on the presentation, contributing factors, diagnosis, and treatment of non-acid reflux. We also propose algorithms for diagnosis and treatment.There is a paucity of recent data regarding non-acid reflux. The recent Porto and Lyon consensus statements do not fully address non-acid reflux or give guidance on classification. However, recent developments in the lung transplantation field, as well as older data in the general population, argue for the importance of non-acid reflux. Extrapolating from the Porto and Lyon consensus, we generally classify pathologic non-acid reflux as impedance events >?80, acid exposure time

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