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LYMPHOMA AND HYPERCALCEMIA IN A PEDIATRIC ORTHOTOPIC LIVER-TRANSPLANT PATIENT
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LYMPHOMA AND HYPERCALCEMIA IN A PEDIATRIC ORTHOTOPIC LIVER-TRANSPLANT PATIENT TRANSPLANTATION Nakazato, P., Esquivel, C. O., URBACH, A. H., Makowka, L., Scantlebury, V., Jaffe, R., Starzl, T. E. 1989; 48 (6): 1003-1006Abstract
We present a case report of a pediatric orthotopic liver transplant recipient who developed lymphoma with hypercalcemia on cyclosporine and prednisone immunosuppression. This is the first reported posttransplant lymphoproliferative disorder complicated by hypercalcemia, with a finding of an elevated 1,25 dihydroxyl vitamin D state, suggesting that it has a role in the pathophysiology of this B cell lymphoma hypercalcemia. The clinical course and management of this disorder with a 31-month follow-up are described.
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