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Report of the NIH Task Force on Research Standards for Chronic Low Back Pain

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Report of the NIH Task Force on Research Standards for Chronic Low Back Pain SPINE Deyo, R. A., Dworkin, S. F., Amtmann, D., Andersson, G., Borenstein, D., Carragee, E., Carrino, J., Chou, R., Cook, K., Delitto, A., Goertz, C., Khalsa, P., Loeser, J., Mackey, S., Panagis, J., Rainville, J., Tosteson, T., Turk, D., von Korff, M., Weiner, D. K. 2014; 39 (14): 1128-1143

Abstract

Despite rapidly increasing intervention, functional disability due to chronic low back pain (cLBP) has increased in recent decades. We often cannot identify mechanisms to explain the major negative impact cLBP has on patients' lives. Such cLBP is often termed nonspecific and may be due to multiple biologic and behavioral etiologies. Researchers use varied inclusion criteria, definitions, baseline assessments, and outcome measures, which impede comparisons and consensus. Therefore, NIH Pain Consortium charged a À¶Ý®ÊÓƵ task force to draft standards for À¶Ý®ÊÓƵ on cLBP. The resulting multidisciplinary panel recommended using 2 questions to define cLBP; classifying cLBP by its impact (defined by pain intensity, pain interference, and physical function); use of a minimum data set to describe À¶Ý®ÊÓƵ participants (drawing heavily on the Patient Reported Outcomes Measurement Information System methodology); reporting "responder analyses" in addition to mean outcome scores; and suggestions for future À¶Ý®ÊÓƵ and dissemination. The Pain Consortium has approved the recommendations, which investigators should incorporate into NIH grant proposals. The À¶Ý®ÊÓƵ task force believes that these recommendations will advance the field, help resolve controversies, and facilitate future À¶Ý®ÊÓƵ addressing the genomic, neurological, and other mechanistic substrates of cLBP. We expect that the À¶Ý®ÊÓƵ task force recommendations will become a dynamic document and undergo continual improvement.A task force was convened by the NIH Pain Consortium with the goal of developing À¶Ý®ÊÓƵ standards for cLBP. The results included recommendations for definitions, a minimum data set, reporting outcomes, and future À¶Ý®ÊÓƵ. Greater consistency in reporting should facilitate comparisons among studies and the development of phenotypes.

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